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The most common man baldness is the androgenetic. It is effecting over 8 million men in Italy between 20 and 40 years old, but it seems that the 88% of the men population is affected somehow during the lifetime, while women are just 5%. The most aggressive form shows up around the 18th year of age; at the beginning there is a great hair loss due to follicle atrophy which isn't able to let grow the hair in good health like before.
The cause for this form of hair loss is a genetic predisposition (hereditary) and this determine a hypersensitivity in the front and parietal part of the scalp of these persons as to the process of the manly hormone (androgenic). Their hair in these areas have a hypesensitivity follicle to these hormones particularly to the diidrotestosterone (DHT). In simple words it happens that the testosterone which is the main manly hormone, gets into the follicle cell and react with an enzyme, the 5-alpha transforming itself in diidrotestosterone. In the bald areas the quality of this enzyme is much higher than the rest of the scalp. Therefore the hair in such areas front and parietal are more sensitive to the action of the diidrotestosterone which makes the hair finer and weaker.
When all this process begins, the immunological system identifies the damaged follicle from the DHT and considering it harmful, it will try to eliminate. Then in such spots it will begin itching, redness and inflammation which will complicate the situation and it will damage the follicle further. The hair will grow up with always more difficulties thinner and weaker untill it will die. In the woman where the androgenic baldness may appear around the 35th year, it seems the hormone DHEA responsible for such baldness. Therefore we deduct that the androgenic alopecia is caused from an action of the androgenic hormones over subjects who are genetically predisposed. This situation is determined by the birth of the person from his chromosomic chart. A scientist who's name is Hamilton, has been among the first one to study this phenomenon and classified the different steps of baldness. Norwood who completed the studies of Hamilton could classify 12 different steps of baldness.
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HAMILTON'S scale
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